Dr. Howard E. Gendelman is the Margaret R. Larson Professor of Internal Medicine and Infectious Diseases, chairman of the Department of Pharmacology and Experimental Neuroscience and director of the Center for Neurodegenerative Disorders at the University of Nebraska Medical Center. Dr. Gendelman is credited with unraveling how functional alterations in brain immunity induce metabolic changes and ultimately lead to neural cell damage across a broad range of infectious, metabolic, and neurodegenerative disorders. These discoveries have had broad implications on developmental therapeutics aimed at preventing, slowing, or reversing neural maladies. He is also credited with demonstrating that AIDS dementia is a reversible metabolic encephalopathy. His work has led to novel immunotherapy strategies for Parkinson's disease that have been successfully tested in early clinical trials as a result of translational investigations.

Prof.Linheng is an international renown scientist in studying stem cells and their associated niches in hematopoietic and intestinal tissues. He was among the first to identify the endosteal niche in supporting hematopoietic stem cell (HSC), the first cellular component of niche identified in a mammalian system. He was also among the first to propose a model of co-existing reserve (a quiescent pool) and active adult stem cells in the same tissue in mammals. This concept not only provides an explanation for controversial observations of both quiescent and cycling stem cells in several tissues including bone marrow, intestine, and hair follicle in mammals, but also accounts for some aspects of drug resistance in cancer. Linheng has contributed to the field by characterizing and demonstrating the roles of several developmental signaling pathways in the regulation of stem cells. These include FGF, IGF, and Notch, BMP, and Wnt signaling pertaining to self-renewal; the PTEN-controlled PI3K-Akt signaling, in coordination with catenin to promote HSC self-renewal, and the role of non-canonical Wnt signaling in maintaining quiescent stem cells. He shows a critical role in epigenetic (via DNA methylation and non-coding RNA) regulation of H19 Igf2 and Gtl2 maintains primitive stem cells via suppression of mitochondrial biogenesis and metabolism; as well as the Hoxb cluster that maintains normal stem cells but also contributes to leukemogenesis. His recent works open possibilities of translational medicine including 1) Robust expanding human umbilical cord blood (UBC) HSCs by targeting Ythdf2, 2) Identification of mesenchymal stem cell (MSC) that facilitates cartilage regeneration, 3) Identification of cancer stem cells immune escaping mechanism mediated by catenin, 4) Tumor-initiating stem cell shape their microenvironment into an immunosuppressive barrier. 5) Development of drugs that target immune escape and immunosuppression. He has filed 6 patterns with 2 pending and 4 granted

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Dr. Benson Edagwa's research is to transform antiretroviral therapies into novel targeted long-acting slow effective-release antiretroviral therapy to facilitate hepatitis B HBV and HIV prevention and treatment strategies. Benson has an extensive background in drug delivery, medicinal chemistry, and pharmacology that includes the development of new strategies for the synthesis of biologically active natural products and their unnatural analogs. He has equal expertise in the design, development, and evaluation of "unique" pro-drugs and drug formulations and their application to human diseases, such as HIV/AIDS, HBV, and tuberculosis. Benson is also one of the Scientific Founders of Exavir Therapeutics Inc. a startup company that is focused on the development of ultra-long-acting therapies for the treatment and prevention of viral infections and addiction. Work from his laboratory and collaborators has demonstrated that daily oral therapies could be transformed into long-acting parenteral formulations to facilitate the prevention and treatment of chronic conditions with no recorded toxicities.

Dr. Elena Poverenov received her Ph.D. in Organic Chemistry at the Weizmann Institute of Science and performed her postdoctoral training in the field of materials chemistry and polymers. In 2011, Elena received an independent research position at Volcani Institute, ARO. Elena's agenda is to introduce advanced materials chemistry and nanotechnology approaches in the field of agriculture, food, and the environment. Her research lab developed several new concepts that made a high general impact on the material and agricultural sciences worldwide. Elena has published more than 50 articles in leading international journals among them the top scientific journals in her research fields and multidisciplinary journals (JACS, Nature, Green Chemistry, ACS Applied Materials & Interfaces, ChemComm, Food Chemistry, Food Hydrocolloids, and more). Elena presented her research at numerous conferences (24 invited lectures) and organized 5 international and 5 local conferences/sessions. For introducing new research directions, Elena received "the Excellent Young Researcher Prize, ARO (2015), "Young Scientist Awardee for Research in Food and Agriculture" International Agropolis and Olam Foundation (2017), Mashov Agriculture Prize (2019), and Igal Alon Prize (2020). Elena was one of the establishers and currently serves as a Head of the Multidisciplinary Agro-nanotechnology and Advanced Materials Research Centre, ARO.

Huang Wei Ling was born in Taiwan, raised and graduated in medicine in Brazil, specialist in infectious and parasitic diseases, a General Practitioner, and a Parenteral and Enteral Medical Nutrition Therapist. Once in charge of the Hospital Infection Control Service of the City of Francis General Hospital, she was responsible for the control of all prescribed antimicrobial medication and received an award for the best paper presented at the Brazilian Hospital Infection Control Congress in 1998. Since 1997, she works with the approach and treatment of all chronic diseases in a holistic way, with treatment guided through the teachings of Traditional Chinese Medicine and Hippocrates. Researcher at the University of Sao Paulo, in the Ophthalmology department from 2012 to 2013.Author of the theory Constitutional Homeopathy of the Five Elements Based on Traditional Chinese Medicine. Author of more than 100 publications about the treatment of a variety of diseases rebalancing the internal energy using Hippocrates' thoughts.

Graduated in Generalist Pharmacy from the University Center of the State of Para, Specialization in Pharmacology from the Federal University of Para and in Clinical Pharmacy and Pharmaceutical Prescription from the Graduate and Graduate Institute, Master in Pharmaceutical Sciences from the Federal University of Para, Doctorate in Pharmaceutical Innovation from the Federal University of Para and Post Doctorate in Tropical Diseases from the Nucleus of Tropical Medicine of the Federal University of Para. He is currently an Adjunct Professor at the Federal University of South and Southeast Para. Accredited as a Professor in the Graduate Program in Pharmaceutical Assistance Level Professional Masters Degree at the Federal University of Para. He is a member of the Brazilian Society of Clinical Pharmacy. He is part of the Working Group on Tropical and Neglected Diseases of the Federal Council of Pharmacy. He has experience in the area of Pharmaceutical Assistance, Clinical Pharmacy, Collective Health, Tropical and Neglected Diseases, Malaria, Therapeutic Control of Antimalarials, and Pharmacogenomics.

EDUCATION: 2020--2022: Ph. D, School of Pharmaceutical Sciences, Shandong University; 2017--2020: M. Sci., School of Pharmaceutical Sciences, Shandong Medical University; 2013--2017: B. Sci., School of Pharmaceutical Sciences, Sichuan Medical University RESEARCH INTERESTS: 1. Design, synthesis and biological evaluation of small molecules against HIV-1 and SARS-CoV-2 virus. 2. Structural modification and structure-activity relationships of butyrylcholinesterase. ADDRESS: School of Pharmaceutical Sciences, Shandong University, No.44, Wenhuaxi Road, Jinan, 250012, P.R.China

Professor in Kunming Institute of Zoology, Chinese Academy of Sciences, China Research Interests： 1. Identification of function components from animal venoms, research and development of medicines; 2. Functional mechanisms of ion channels (Na+, K+, Ca2+, Cl-, TRP); 3. Mechanisms of human diseases such as thrombosis, pain, autoimmune disease and epilpsia． As the corresponding author, Dr Lai Ren has published more than 200 papers in international journals, such as Immunity, Nature Immunology, Blood, Circulation Research, Cell Research, Science Advances, PLoS Biology, Nature Communications, Chemical Reviews, and Proc. Natl. Acad. Sci.

Dr. Shanshan Zhao is a senior pharmacist at China Emergency General Hospital, also a Good Clinical Practice (GCP) inspector for China National Medical Products Administration. When she was a Ph.D. candidate, she did research about nanoparticle based drug delivery system. After she joined in China Emergency General Hospital, she has been the drug and medical device clinical trial institution secretary and she has participated in hundreds of drug and medical device clinical trials. And now she is doing stem cells research in Agency for Science, Technology and Research in Singapore. Dr. Shanshan Zhao is competent in both basic medical research and clinical medical research. She is also a thesis supervisor for some MSc students.

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Ahmad Zare Javid, Associate Professor Ahmad Zare Javid is the Head of the Department of Nutrition and an associate professor in the School of Allied Medical Sciences at Ahvaz Jundishapur University of Medical Sciences, Iran, holding a Ph.D. in nutrition sciences and graduated from Newcastle University, UK. His research interests are mainly on Nutrition, Diabetes mellitus, and its complications, antioxidants, nutrition, oral health, periodontal disease, metabolic syndrome, obesity, sports nutrition, etc. He has a number of publications and undergoing research in these fields. He is also teaching several nutritional modules advanced nutrition, nutrition counseling and education, nutrition physiology, nutrition, oral health, nutrition during the lifespan, Nutrition for specific groups, advanced English, and medical nutrition therapy, for Ph.D., MSc, and BSc students. He is also a thesis supervisor for some Ph.D., MSc, and BSc students.