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Professor and Vice-Chair for Research, Department of Biochemistry & Molecular Biology; Professor (Courtesy), Surgery/Urology and Eppley Cancer Institute, University of Nebraska Medical Center (UNMC), Omaha, NE, USA

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Dr. Luisa Maria Botella Research Scientist at the Margarita Salas Biological Research Centre (CIB), belonged to the research agency of the Spanish National Research Council (CSIC) for 30 years; 20 of them were dedicated to research on Rare Diseases. Patient representative in the European Network on Rare Vascular Diseases, (PAG VASC-ERN) and Member of the International Commission on Medical Advice and Research of Hereditary Hemorrhagic Telangiectasia (Global Research and Advisory board, GRMAB). Member of FEDER (Spanish Federation for Rare Diseases), HHT Spain, and European Federation of HHT. The research focused on rare diseases with vascular involvement (HHT, CCM, VHL, and PPGL).

Vasudevanpillai Biju studied chemistry at CSIR-RRL and the University of Kerala and obtained his Ph.D. in 2000. After postdoctoral research in Japan and the US, he was a scientist in AIST, Japan. In parallel, he was a visiting scientist at the University of Texas at Austin and a JST PRESTO Researcher. Since February 2016, he has been a Professor at Hokkaido University. His research interests include semiconductor quantum dots, photo-functional molecules, and single-molecule techniques. His research activities are recognized with various awards by the Ozaki Foundation (Gennai Award), the Japanese Photochemistry Association, the Asian and Oceanian Photochemistry Association, and the Chemical Society of Japan. In 2011 he was elected as a Fellow of the Royal Society of Chemistry.

Dr. Helena Moreira is an Assistant Professor in the Department of Basic Medical Science of the Faculty of Pharmacy at the Wroclaw Medical University (Poland). She completed her doctoral studies at the Institut Gilbert-Laustriat (at DepartementPhysicochimie des Interactions Cellulaires et Moleculaires) in Strasbourg in France where she was working on the molecular mechanisms of TNF secretion, a key cytokine in chronic inflammation. Dr. Moreira is deeply interested in researching cancer treatment, especially in studying the anti-cancer mechanisms of various natural plant extracts and polyphenols. She has an extensive experience in cancer research, cell cultures, and flow cytometry. Currently, her interests focus on cancer stem cells, especially colorectal cancer. She is the organizer of many pieces of training and conferences and participates in many research projects.

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Dr. Jiaqian Wu received her Ph.D. training from the Molecular and Human Genetics Program at Baylor College of Medicine and completed postdoctoral training at Yale and Stanford University. She made significant contributions to the Human Genome Project, Rat Genome Project, NIH Mammalian Gene Collection effort, and ENCODE project. Dr. Wu employed interdisciplinary approaches including molecular and cellular biology and genomics to study gene transcription and regulation. She was one of the first to use RNA-Seq to characterize the stem cell neural differentiation process. Additionally, her group carried out unprecedented transcriptome profiling for purified neurons, glia, and vascular cells from the brain by RNA-Seq. Her lab identified many novel long noncoding RNAs (lncRNAs), and their functional and genetic experiments substantiated the role of lncRNA in oligodendrocyte precursor cell (OPC) formation for the first time. Furthermore, the Wu lab also investigated protein-coding and lncRNA gene expression and regulation in spinal cord injury phases in mouse and rat models. These results have been published in the Journal of Neuroscience, PNAS, Cell Reports and Nature Neuroscience, etc. Wu lab deposited their RNA-Seq datasets in the database (http://jiaqianwulab.org/resource.htm) freely accessible to the research community.

Zeliha Selamoglu is a Professor in the Medical Biology department of Nigde Omer Halisdemir University, Turkey. She earned her Ph.D. in Biology from Inonu University, She has published over 200 peer-reviewed journal articles with over 3510 citations and many technical reports. She is a member of the Society for Experimental Biology and Medicine: Associate Membership and European association for cancer research. She has served as an Editorial Board member for many Journals

Dr. Marika Cordaro graduated in Biology from the University of Messina in 2015. She completed his Ph.D. in Applied Biology and Experimental Medicine at the Department of Biological and Environmental Sciences at the University of Messina, Italy in the year 2017. She is a young researcher in physiology, with a particular interest in cell physiology and molecular mechanism underlying inflammation. In particular, Dr. Cordaro, during her research activity, produced about 134 articles that attest to a diffuse interest in the field of inflammation and oxidative stress neurological disorder-related. She is also interested in endocrine disruptors and in their role in neurological deficits. Her research is involved in preclinical studies for the discovery of physiological cellular responses that could be used as new potential therapeutic targets. Dr. Cordaro has knowledge about animal research, behavioral alterations, biochemical and molecular biology, and immunohistochemical analysis. Additionally, she has been serving as an editorial board member of several cited journals.

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Jina Ko is an Assistant Professor in the Departments of Pathology and Laboratory Medicine and Bioengineering at the University of Pennsylvania. She focuses on developing single molecule detection from single extracellular vesicles (EV) and multiplexed molecular profiling to better diagnose diseases and monitor treatment efficacy. Jina graduated from Rice University with a B.S. in Bioengineering and a B.A. in French Studies in 2013 and she earned her Ph.D. in Bioengineering at the University of Pennsylvania in 2018. During her Ph.D., she developed machine learning-based microchip diagnostics that can detect blood-based biomarkers to diagnose pancreatic cancer and traumatic brain injury. For her postdoctoral training, she worked at Massachusetts General Hospital and the Wyss Institute at Harvard University as a Schmidt Science Fellow and an NIH K99/R00 award recipient. Jina developed new methods to profile single cells and single EVs with high throughput and multiplexing.

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Dr. Natalia Glatzel Plucinska has a master's degree in molecular biology and a Ph.D. in medical sciences. She works as a researcher at the Wroclaw Medical University. She has experience in molecular biology, cell culture, flow cytometry, and digital image analysis. In her research, she focuses mainly on the molecular basis of cancer progression and metastasis. Her recent studies concern the role of SATB1 and Haspin expression in non-small cell lung cancers. Additionally, she is involved in research on breast cancer adoptive immunotherapy. She is a co-author of 22 papers and participates in numerous research projects.

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Dr. Mahaling received her Doctorate degree in Biological Sciences and Bioengineering from the Indian Institute of Technology Kanpur (IITK), India. She has postdoctoral training from the Department of Chemical Engineering at the IITK, the Wilmer Eye Institute at the Johns Hopkins University School of Medicine, and the Department of Chemical, Biochemical and Environmental Engineering at the University of Maryland Baltimore County, and the Department of Ophthalmology and Visual Sciences, Medical College of Wisconsin. She has published several first-author peer-reviewed articles and has been a reviewer of prestigious journals including ACS journals and IOP journals. She has won numerous awards including American Diabetic Association Postdoctoral Fellow Award, 2020; ISCA Young scientist award in medical sciences including physiology, 2014 among others. She is the recipient of several travel grants and prestigious national and international fellowships. The use of nanomaterials has revolutionized the fields of medicine, toxicology, and pharmacology. With expertise in these multidisciplinary fields, Dr. Mahaling's research interest lies in the basic as well as translational approaches for diabetes-related neurovascular degenerations and retinal diseases with an ultimate goal is to identify therapeutic targets, development, evaluation, and validation of effective, potential next-generation therapeutics. Dr. Mahaling uses cutting-edge technologies to develop novel therapeutics and nanoparticle-based drug delivery systems.

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Biography of presenting author: Master's degree in Biological Sciences, Ph.D. in "Experimental Medicine", Associate Professor in Clinical Biochemistry and Clinical Molecular Biology at Messina University, Dpt of Chemical, Biological, Pharmaceutical, and Environmental Sciences. She has an important research background in the fields of inflammation, neuroinflammation, oxidative stress, pain, immunity in specific areas of biochemistry, pharmacology, and neuroscience, and nutrition Research interests: biochemistry, pharmacology, nutrition No. of published articles and Journal information: about 150 publications, in international peer-reviewed journals such as Antioxidants, IJMS, Faseb, etc.

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Mohamed H. Yousef has completed his master's degree in 2022 from the American University in Cairo. He is currently a research assistant and a Ph.D. fellow at the Institute of Global Health and Human Ecology (IGHHE) at the American University in Cairo. He has been working on several research projects spanning the basic and clinical arenas. He authored/co-authored a number of well-cited articles in peer-reviewed journals. His research interests comprise exploring the pathophysiological underpinnings of neurodegenerative/neuroinflammatory disorders and exploiting these for developing novel theranostic platforms. Mohamed's thesis project constituted a central research endeavor of Dr. Anwar Abdelnaser's lab at the IGHHE and inspired other work by new lab members. The premise of the work entailed exploring a three-fold therapeutic utility of GSK3 inhibition in neurodegenerative diseases, where selective targeting of the GSK3 paralogs was conducive to anti-inflammatory and anti-oxidative outcomes, over and above its established modulation of the underlying protein pathology.

Dr. Ramona D Amico completed a bachelor's degree in biological sciences and a master's degree in biology at the University of Messina in 2016. Dr. Ramona D Amico completed her Ph.D. in Applied Biology and Experimental Medicine in the year 2020 at the University of Messina. Additionally, she worked at the Health Science Research Centre, Whiteland College, the University of Roehampton in London (UK), and performed postdoctoral studies at the University of Messina. She worked as a researcher for studies on preclinical pharmacology activities (in vitro primary cultures and in vivo experimental models), for the Epitech Group; she is also a research fellow in Biochemistry at Messina University. Now she is a Researcher at the University of Messina. She has published more than 70 articles in reputed journals about biochemistry, oxidative stress, and pharmacology. Her research is involved in preclinical studies for the discovery of new biochemical markers. Dr. Ramona D'Amico has knowledge about animal research, biochemical and molecular biology, and immunohistochemical and immunofluorescence analysis.

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Dr. Lee received his BS in Biomedical Engineering from Inje University (South Korea) in 2002. He completed his Ph.D. in Biomedical Engineering from Columbia University in 2010 and received postdoctoral training until 2014 at the Center for Craniofacial Regeneration in the College of Dental Medicine. Dr. Lee is currently an Assistant Professor of Craniofacial Engineering (in Dental Medicine). Dr. Lee's research is focused on musculoskeletal and craniofacial tissue regeneration by harnessing endogenous stem/progenitor cells using advanced scaffold systems, control-delivery systems, and translational animal models. In his early research career, Dr. Lee developed an innovative strategy for tissue regeneration by homing the body's own stem cells into defect sites. He applied the new strategy for successful regeneration of synovial joint condyle, tendons, and knee meniscus resulting in publications in prestigious journals, including The Lancet, Science Translational Medicine, and Journal of Clinical Investigation. His recent publication in the Journal of Clinical Investigation was highlighted in the New England Journal of Medicine in 2016. For the last 10 years of his research career including graduate programs, Dr. Lee's publications have been cited over 2,200 times (as of Sept 2017), showing the high impact of his research in the field. Dr. Lee is a recipient of the New Investigator Recognition Award at Orthopedic Research Society (2013), Best Research Mentor Award from Bergen Academy (2011), Webster Jee Young Investigator Award at International Chinese Hard Tissue Society (2009), Young Investigator Award at Society of Physical Regulation in Biology and Medicine (2008), University Dean Award from Inje University (2004), and an international fellowship award from Korea Science and Engineering Foundation (2003). He was an invited speaker at Society for Biomaterials (2014) and Gordon Research Conference on Collagen (2011). He served as an invited moderator and reviewer at the annual meeting of the Orthopedic Research Society (2016) and a journal reviewer for the Journal of Clinical Investigation, Journal of Orthopedic Research, Tissue Engineering, Biomaterials, and Macromolecular Bioscience, Plos One, Advanced Healthcare Materials, and more. Dr. Lee was a member of the NIH BTSS study section (2015), a grant review panel in the Maryland Industrial Partnerships Program (MIPS) (2016), and the European Research Council (2017). To date, Dr. Lee has mentored over 30 post-graduate, dental and undergraduate students. Many of his students received research awards, including Birnberg research awards, AADR fellowship award, ASDA best presentation award, Melvin Morris Awards, and Hatton Award finalist.

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PROF. HANNA ENGELBERG-KULKA was born in Vienna, Austria. She completed her MSc degree and Degree-Ph.D on the subject (Studies on streptomycin-dependent bacteria) at Hebrew University, Jerusalem, Israel and She is a Member, of the Executive Committee of the Board of Governors, Hebrew University, from 1994-2000 Chairperson, Dept of Molecular Biology, Institute of Microbiology, she was honored with the EMET prize on Genetics and The Ilanit-Kazir Prize awarded once in 3 years by the Israel Society of Experimental Biology (FISEB). This award is given to Hanna Engleberg Kulka for her pioneering research that led to the discovery of bacterial PCD and its mode of signaling, the identification of a communication factor, and The Ulizky Prize of the Israel Society of Microbiology for Excellency in microbiological research. She published 115 publications in first-class journals. Also, she is an Invited speaker for International Scientific Meetings; for the last 28 years, Her research areas are Molecular biology, Microbial genetics, biochemistry, and physiology Since 1996